Can Treatment Alter The Natural History Of MS?

Most MS researchers believe that it can, but there are few studies that confirm this impression.

More than 4,000 patients were followed for about 6 years, and those who were treated had lower disability scores than a natural history cohort. The reduction was 25% to 40% depending on the type of measurement. Improvement in quality of life measures showed an even greater difference of 40% to 45%. The lead author, Dr Jacqueline Palace, a neurologist at the University of Oxford in the UK, observed that if this effect is sustained over 20 years, treatment would be “cost-effective,” using a predefined target of about $50,000 per quality-adjusted life-year.

Dr. Jack Florin, MD

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