Monoclonal antibodies are the most important new experimental treatment for migraine. They target the calcitonin gene-related peptide (CGRP). When a migraine patient is having an attack, this compound is increased in the blood and not so between attacks. Injecting this compound into a migraine patient always triggers an attack.
There are 3 monoclonal antibodies to CGRP being tested. Preliminary results seem positive and side effects very low. Our center is currently recruiting for a trial of the compound termed LY2951742. This is a phase II trial, but there are already plans for a phase III trial with the hope of obtaining FDA indication and making this medication available to all migraine patients.
Contact our center for further information about the trial.
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